Poultry Trends - 2019 - 13

5 facts about alpha-monolaurin
Alpha-monolaurin possesses unique properties,
which enables it to stimulate animal health via multiple actions
In the fight against increasing antibiotic
resistance, many countries have banned the
systematic use of antibiotics in animal feed.
Producers are looking for alternatives to
maintain animal health and performance.
Medium-chain fatty acids (MCFAs) are a good
alternative, but glycerides of these MCFAs are
even more interesting because of their unique
properties. This applies in particular to
alpha-monolaurin (C12). Find out why.
FRAmelco R&D

1. Stronger than free MCFAs

Alpha-monolaurin is produced by an esterification
reaction between lauric acid and glycerol creating
a covalent bond between these two molecules. It
showed to possess strong antibacterial properties,
especially against Gram-positive pathogenic
bacteria. Alpha-monolaurin interferes with the cell
membrane and disturbs vital cell processes of the
bacteria.

Globally, alpha-monolaurin is applied to
suppress the negative impact of Marek's disease,
Newcastle disease, infectious bronchitis, avian
influenza and others.

4. Boosting effect on immune response

For optimal animal health and performance, a
properly working immune system is crucial. This
means it responds correctly to diseases, but does
not overreact when small challenges occur. Such
overreaction can be very costly for the animal,
restricting the possibility to reach its genetic growth
potential. In vivo trials revealed alpha-monolaurin
can improve the immune response of infectious
bronchitis vaccinated broilers. In vitro results
confirm the potential anti-inflammatory properties
of alpha-monolaurin (Figure 1).
40
Alpha-monolaurin

OTC
30

The specific molecular structure enables
alpha-monolaurin to remain in its active form
during passage of the animal's intestinal tract. This
is explained by the high pKa value (13.62), which
is the pH at which a molecule is dissociated for
50%. Knowing that the pH in the gastro-intestinal
tract of the animal never reach such a high pH,
apha-monolaurin can be considered pH
independent and will not dissociate in the gastrointestinal tract. In addition, alpha-monoglycerides
are not susceptible to enzymatic breakdown.

3. Strong against viruses

Alpha-monolaurin is gaining more interest in the
fight against viral diseases. Its molecular structure
makes it able to attack fat-enveloped viruses by
destroying their fat-envelope. Several in vitro trials
reveal that the anti-viral effect of glycerides of lauric
acid are outperforming glycerides of other MCFAs.

µM NO

2. Active in the entire intestinal tract

20

10

1

10

100

1000

0

PPM

Figure 1: Effect of alpha-mono-, di- and triglycerides of C12,
and oxytetracycline on nitric oxide (NO) production of
macrophage-like cells induced by LPS challenge.

5. Antibiotic reduction

As a result of the multiple actions of alphamonolaurin, this feed additive is a successful tool
in antibiotic free diets. One will notice a reduction
in curative antibiotic usage as well as an improved
animal health and performance with the use of
alpha-monolaurin. References are available upon
request.

ADVERTISEMENT



Poultry Trends - 2019

Table of Contents for the Digital Edition of Poultry Trends - 2019

Poultry Trends - 2019
Contents
Latest poultry, egg market forecasts available in 2019 WATT Executive Guide to World Poultry Trends
World poultry production to top 128 million tons in 2019
Slow poultry growth driven by developing countries’ demand
Brazil, China, US lead poultry meat production to 2028
World egg production reaches 80-million-metric-ton mark
How poultry trade volumes differ around the world to 2028
WATT AgNet Top Companies: Top world broiler, egg rankings for 2019
World’s Top Feed Companies: 102 companies rise to the top in 2018..
Global egg consumption rising with changing diets
Poultry Trends - 2019 - Poultry Trends - 2019
Poultry Trends - 2019 - Cover2
Poultry Trends - 2019 - 1
Poultry Trends - 2019 - Contents
Poultry Trends - 2019 - 3
Poultry Trends - 2019 - Latest poultry, egg market forecasts available in 2019 WATT Executive Guide to World Poultry Trends
Poultry Trends - 2019 - 5
Poultry Trends - 2019 - World poultry production to top 128 million tons in 2019
Poultry Trends - 2019 - 7
Poultry Trends - 2019 - 8
Poultry Trends - 2019 - 9
Poultry Trends - 2019 - 10
Poultry Trends - 2019 - 11
Poultry Trends - 2019 - 12
Poultry Trends - 2019 - 13
Poultry Trends - 2019 - Slow poultry growth driven by developing countries’ demand
Poultry Trends - 2019 - 15
Poultry Trends - 2019 - 16
Poultry Trends - 2019 - 17
Poultry Trends - 2019 - 18
Poultry Trends - 2019 - 19
Poultry Trends - 2019 - Brazil, China, US lead poultry meat production to 2028
Poultry Trends - 2019 - 21
Poultry Trends - 2019 - 22
Poultry Trends - 2019 - 23
Poultry Trends - 2019 - 24
Poultry Trends - 2019 - 25
Poultry Trends - 2019 - 26
Poultry Trends - 2019 - 27
Poultry Trends - 2019 - 28
Poultry Trends - 2019 - 29
Poultry Trends - 2019 - World egg production reaches 80-million-metric-ton mark
Poultry Trends - 2019 - 31
Poultry Trends - 2019 - 32
Poultry Trends - 2019 - 33
Poultry Trends - 2019 - 34
Poultry Trends - 2019 - 35
Poultry Trends - 2019 - 36
Poultry Trends - 2019 - 37
Poultry Trends - 2019 - 38
Poultry Trends - 2019 - 39
Poultry Trends - 2019 - How poultry trade volumes differ around the world to 2028
Poultry Trends - 2019 - 41
Poultry Trends - 2019 - 42
Poultry Trends - 2019 - 43
Poultry Trends - 2019 - 44
Poultry Trends - 2019 - 45
Poultry Trends - 2019 - WATT AgNet Top Companies: Top world broiler, egg rankings for 2019
Poultry Trends - 2019 - 47
Poultry Trends - 2019 - 48
Poultry Trends - 2019 - 49
Poultry Trends - 2019 - 50
Poultry Trends - 2019 - 51
Poultry Trends - 2019 - 52
Poultry Trends - 2019 - 53
Poultry Trends - 2019 - World’s Top Feed Companies: 102 companies rise to the top in 2018..
Poultry Trends - 2019 - 55
Poultry Trends - 2019 - 56
Poultry Trends - 2019 - 57
Poultry Trends - 2019 - Global egg consumption rising with changing diets
Poultry Trends - 2019 - 59
Poultry Trends - 2019 - 60
Poultry Trends - 2019 - 61
Poultry Trends - 2019 - 62
Poultry Trends - 2019 - 63
Poultry Trends - 2019 - 64
Poultry Trends - 2019 - Cover3
Poultry Trends - 2019 - Cover4
http://www.poultrytrends.com/201911
http://www.poultrytrends.com/201811
http://www.poultrytrends.com/201711
http://www.poultrytrends.com/2016
http://www.poultrytrends.com/2015
http://www.poultrytrends.com/2014
http://www.poultrytrends.com/2013
http://www.poultrytrends.com/2012
http://www.nxtbookMEDIA.com